Colloid milium is a wholesale led serial lights rare condition characterized by (1) the presence of multiple, dome-shaped, amber- or flesh-colored papules developing on light-exposed skin and (2) the observance of dermal colloid under light microscopy.

Colloid milium is more common in fair-skinned individuals. Colloid has a distinct electron microscopic appearance, which helps to distinguish it from amyloid. Colloid milium (CM) is a rare cutaneous deposition disease with at least 3 distinct subtypes. Colloid milium (CM) is a rare cutaneous deposition disorder characterized by the presence of multiple dome-shaped. Colloid milium is a degenerative condition linked to excessive sun exposure and possibly exposure to petroleum products and hydroquinone.

Lesions are usually asymptomatic aside from occasional pruritus and are only distressing to patients due to their unsightly appearance. Pigmented colloid milium has a distinct clinical presentation. Colloid milium can involve upper eyelids in isolation, sparing the lower eyelids and facial skin. Such rare presentations should be kept in mind while examining similar lesions. Some entities to consider in the differential include systemic amyloidosis, primary cutaneous amyloidosis, syringomas, sarcoidosis, steatocystoma multiplex, lipoid proteinosis, molluscum contagiosum, papular mucinosis, and sebaceous hyperplasia. Dermabrasion, cryotherapy, and diathermy have been tried with limited success.

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